abstract：:A deletion/insertion polymorphism in the ACE gene has been reported previously as a potent factor for myocardial infarction. We have tested the frequency of the deletion (D) allele of the ACE gene in 308 consecutive patients admitted to coronary care with chest pain. The gene frequencies were compared with those of 34...

journal_title：Journal of human hypertension

authors： Leatham E,Barley J,Redwood S,Hussein W,Carter N,Jeffery S,Bath PM,Camm A

更新日期：1994-08-01 00:00:00

abstract：:The aim of the present longitudinal study was to describe determinants of blood pressure (BP) and echocardiographically calculated left ventricular mass in adolescents with a variable risk of future hypertension. BP was measured and M-mode echocardiography was performed in 52 children, 29 male and 23 female, at a mean...

journal_title：Journal of human hypertension

authors： Himmelmann A,Svensson A,Hansson L

更新日期：1994-07-01 00:00:00

abstract：:In a 10 year prospective study, we investigated the utility of the level of serum gamma-glutamyl transferase (GGT), a biological marker of alcohol consumption, in predicting the development of hypertension in Japanese male drinkers, all of whom lived in a rural community. The study included 77 men, aged 30-69 years, w...

journal_title：Journal of human hypertension

authors： Miura K,Nakagawa H,Nakamura H,Tabata M,Nagase H,Yoshida M,Kawano S

更新日期：1994-06-01 00:00:00

abstract：:A total of 78 Chinese patients with clinically uncomplicated non-insulin-dependent diabetes (NIDDM) who had plasma creatinine concentrations of < 150 mumol/l were studied. Antihypertensive treatment was discontinued for at least six weeks prior to measurements of routine biochemistry, proteinuria, plasma atrial natriu...

journal_title：Journal of human hypertension

authors： Chan JC,Cheung CK,Cockram CS,Critchley JA,Swaminathan R,Law LK,Nicholls MG

更新日期：1994-06-01 00:00:00

abstract：:It has been suggested that risks of hypertension and cardiovascular disease begin in utero and that maternal nutrition plays an important role. We have examined the relation between maternal factors and BP in a study of 1,311 children in which physical measurements at 9-11 years of age have been linked to a parental q...

journal_title：Journal of human hypertension

authors： Whincup P,Cook D,Papacosta O,Walker M,Perry I

更新日期：1994-05-01 00:00:00

abstract：:Nineteen patients with essential hypertension on regular treatment with nifedipine tablets 20 mg twice daily and whose DBP was < 95 mmHg on at least two occasions two weeks apart were entered in a double-blind randomised crossover study of three weeks treatment with nifedipine coat core (new formulation) either as 30 ...

journal_title：Journal of human hypertension

authors： Missouris CG,Cappuccio FP,Markandu ND,Singer DR,MacGregor GA

更新日期：1994-04-01 00:00:00

abstract：:The objective of this study was to investigate the relationships between erythrocyte Na-Li countertransport, plasma renin activity (PRA), plasma aldosterone and plasma atrial natriuretic peptide (ANP) in a population-based study, in a cross-sectional observation of a randomly selected sample of a male working populati...

journal_title：Journal of human hypertension

authors： Strazzullo P,Cappuccio FP,Miller MA,Buckley MG,Sagnella GA,Trevisan M,Pagano E,MacGregor GA

更新日期：1994-03-01 00:00:00

abstract：:In a 12 week randomised, double-blind study, a total of 31 patients with a sitting DBP of between 95 and 115 mmHg were enrolled for comparison of the antihypertensive, metabolic and antiplatelet effects of the drugs cilazapril and nifedipine retard. A two week placebo treatment was given before either cilazapril (2.5 ...

journal_title：Journal of human hypertension

authors： Ding YA,Law HW,Chou TC

更新日期：1994-02-01 00:00:00

abstract：:Various beta-adrenergic receptor antagonists have different effects on myocardial function. A clinical study was performed in 30 patients with symptomatic coronary artery disease and systemic hypertension to compare the effects of single intravenous doses of 0.15 mg/kg celiprolol (n = 16) (third generation beta-blocki...

journal_title：Journal of human hypertension

authors： Modersohn D,Franz N,Heublein B,Panzner B,Walde T,Bruch L

更新日期：1994-02-01 00:00:00

abstract：:To clarify the natriuretic action of endogenous atrial natriuretic peptide (ANP) in patients with essential hypertension (EHT), we examined the relationship between ANP release and urinary sodium excretion in response to hypertonic saline infusion. Plasma ANP levels increased from 13.3 +/- 2.0 pg/ml to 37.0 +/- 3.0 pg...

journal_title：Journal of human hypertension

authors： Akaike M,Nishiuchi T,Matsumoto N,Kawai H,Saito S

更新日期：1994-01-01 00:00:00

abstract：:Coronary heart disease (CHD) is still relatively uncommon in the black population of South Africa. We embarked on a study to determine the prevalence of risk factors leading to CHD in the black population of Durban. The study sample was selected from patients attending a dental clinic at a hospital. A total of 458 Zul...

journal_title：Journal of human hypertension

authors： Seedat YK,Mayet FG,Latiff GH,Joubert G

更新日期：1993-12-01 00:00:00

abstract：:Despite the availability of multiple nonpharmacological and pharmacological antihypertensive regimens large scale control of BP on a population basis is still unsatisfactory. To achieve a better quality in hypertension care we have developed and evaluated a structured outpatient hypertension treatment and teaching pro...

journal_title：Journal of human hypertension

authors： Sawicki PT,Mühlhauser I,Didjurgeit U,Berger M

更新日期：1993-12-01 00:00:00

abstract：:To investigate the involvement of the sympathetic nervous system and cell membrane sodium transport in hypertensive cardiac hypertrophy, we divided 51 middle-aged male patients with essential hypertension into cardiac hypertrophy and noncardiac hypertrophy groups. We then compared the plasma noradrenaline concentratio...

journal_title：Journal of human hypertension

authors： Saito T,Kai N,Yamamoto K,Iwata J,Deguchi F,Inagaki Y

更新日期：1993-10-01 00:00:00

abstract：:The relationship between cardiovascular risk factors and urine albumin excretion were studied in 474 healthy office workers. Albumin concentration was measured fresh in first morning midstream urines. Lifestyle details, oscillometric BP and lipids were assessed. Subjects with urine albumin concentration above the medi...

journal_title：Journal of human hypertension

authors： Dimmitt SB,Lindquist TL,Mamotte CD,Burke V,Beilin LJ

更新日期：1993-06-01 00:00:00

abstract：:Erythrocyte Na/K flux ratio was examined in relation to a family history of essential hypertension (FH-HT) and plasma and urine electrolytes in 84 normotensive children (13-15 yrs old), and in relation to sodium intake in six children with acute glomerulonephritis or IgA nephropathy who had normal renal function (6-13...

journal_title：Journal of human hypertension

authors： Uchiyama M,Satokata I

更新日期：1993-02-01 00:00:00

abstract：:The treatment of hypertension is based on an assessment of the balance between the effects of therapy on survival on the one hand and effects of the patient's symptoms and well-being on the other. The concept of quality of life is used to summarise the latter effects. Preservation of quality of life involves both the ...

journal_title：Journal of human hypertension

authors： Jern S,Zanchetti A

更新日期：1993-02-01 00:00:00

abstract：:It has been claimed that calcium lowers BP. The present randomised, double-blind, placebo-controlled crossover study is the first to investigate the effect on BP of a high oral dose of calcium given for a long period to patients with previously untreated hypertension. Elemental calcium (2 g) was administered for 12 we...

journal_title：Journal of human hypertension

authors： Galløe AM,Graudal N,Møller J,Bro H,Jørgensen M,Christensen HR

更新日期：1993-02-01 00:00:00

abstract：:Diabetes mellitus (DM)-linked metabolic alterations and hypertension concomitantly accelerate or precipitate cerebrovascular and coronary heart disease, nephropathy, retinopathy and widespread macroangiopathy, thereby conferring to diabetic patients a very high risk of morbidity, disability and early death. Therefore,...

journal_title：Journal of human hypertension

authors： Weidmann P,Boehlen LM,de Courten M,Ferrari P

更新日期：1992-12-01 00:00:00

abstract：:For nearly two decades, the National High Blood Pressure Education Programme has administered a programme of public, patient, and professional education in an effort to reduce uncontrolled hypertension, an important public health problem in the USA. A broad network has been established and many partners have joined fo...

journal_title：Journal of human hypertension

authors： Roccella EJ,Lenfant C

更新日期：1992-12-01 00:00:00

abstract：:Seventeen untreated and 36 treated hypertensives aged 65 years or more were referred to our clinic because of repeated values of systolic blood pressure > or = 160 mmHg and diastolic blood pressure > or = 95 mmHg. All 53 patients underwent 24h blood pressure monitoring during their customary daily activities. Eleven (...

journal_title：Journal of human hypertension

authors： Wittenberg C,Zabludowski JR,Rosenfeld JB

更新日期：1992-10-01 00:00:00

abstract：:The haemodynamic effects of 45 min of treadmill exercise (at 70% of resting heart rate reserve) were determined in 5 young adults with hypertension and rapid resting heart rates (greater than 90 beats/min in clinic) and were compared with those of 5 age-matched normotensive subjects. Blood pressure was lower after exe...

journal_title：Journal of human hypertension

authors： Floras JS,Wesche J

更新日期：1992-08-01 00:00:00

abstract：:Hypertension is a known risk factor in the genesis of coronary artery disease. However, the effect of pre-existing hypertension on the long-term mortality in patients with established coronary heart disease is not clear. The present cohort study analysed the influence of baseline mild to moderate treated hypertension ...

journal_title：Journal of human hypertension

authors： Gupta R,Gupta KD,Kasliwal P

更新日期：1992-08-01 00:00:00

abstract：:We have studied prospectively the acute blood pressure lowering effect on an oral dose of captopril, 25 mg in 240 hypertensive patients. The mean relative reduction of systolic and diastolic BP was 16 and 15% respectively and the mean time to the mean arterial pressure nadir was 59 minutes. Systolic BP fell by more th...

journal_title：Journal of human hypertension

authors： Postma CT,Dennesen PJ,de Boo T,Thien T

更新日期：1992-06-01 00:00:00

abstract：:A 16 year old boy presented with accelerated hypertension and urinary tract obstruction caused by phimosis. Relief of the obstruction by circumcision reversed the hypertension. We believe that accelerated hypertension secondary to phimosis has not previously been described. ...

journal_title：Journal of human hypertension

authors： Robinson FO,Johnston SR,Atkinson AB

更新日期：1992-04-01 00:00:00

abstract：:The aim of this study was to evaluate the effect of antihypertensive treatment with doxazosin on left ventricular anatomy and function. Therefore, after 4 weeks of washout with placebo (phase 1), doxazosin (dosage range from 1 to 16 mg, plus hydrochlorothiazide when necessary) was given to 11 essential hypertensive pa...

journal_title：Journal of human hypertension

authors： Agabiti-Rosei E,Muiesan ML,Rizzoni D,Zulli R,Calebich S,Beschi M,Castellano M,Muiesan G

更新日期：1992-02-01 00:00:00

abstract：:Persistence in ranks (tracking) for blood pressure and anthropometric measures over a one year period was examined in 208 Nigerian children (age 6-17 years). Systolic blood pressure tracked better than diastolic blood pressure (r = 0.52 to 0.72) and r = 0.25 to 0.55, respectively). For systolic blood pressure, 56.5%-7...

journal_title：Journal of human hypertension

authors： Adams-Campbell LL,Ukoli FA,Silverman JA,Omene JA,Nwankwo MU,Kuller LH

更新日期：1992-02-01 00:00:00

abstract：:The purpose of this study was to examine the pattern of diurnal variation of blood pressure in normotensive working women, and to assess the effect of work stress on this pattern. The subjects were 121 normotensive (based on clinic readings less than 140/90 mmHg) young women (age = 30.2 +/- 7.3 years; range 20-50) who...

journal_title：Journal of human hypertension

authors： James GD,Moucha OP,Pickering TG

更新日期：1991-12-01 00:00:00

abstract：:A total of 930 patients have been evaluated for safety in a programme of clinical trials for lisinopril-hydrochlorothiazide combination treatment. Combination therapy with these two agents is generally well tolerated. In clinical trials, adverse experiences in patients treated with a lisinopril-hydrochlorothiazide com...

journal_title：Journal of human hypertension

authors： Murray NH

更新日期：1991-12-01 00:00:00

abstract：:In addition to high blood pressure, hypertension is characterised by metabolic and cardiovascular abnormalities, including decreased arterial compliance. To evaluate arterial involvement in early hypertension, we have employed a technique that analyses the arterial pulse wave contour to separately quantify proximal co...

journal_title：Journal of human hypertension

authors： Weber MA,Smith DH,Neutel JM,Graettinger WF

更新日期：1991-10-01 00:00:00

abstract：:Hypertension may influence the atherosclerotic process of large arteries via pressure and shear forces. The pressure force dilates and stiffens arteries because of the non-linear elastic behaviour of arterial walls. This partly explains the increased diameter and decreased compliance of the brachial artery in hyperten...

journal_title：Journal of human hypertension

authors： Simon AC,Pithois-Merli I,Levenson J

更新日期：1991-08-01 00:00:00

abstract：:This study reports a correlation of alkaline phosphatase (AP) with diastolic blood pressure (DBP), and a reduction of alkaline phosphatase after chlorthalidone therapy that reached a nadir at three years of therapy, then gradually returned toward, but not reaching, baseline values. The data is from the baseline examin...

journal_title：Journal of human hypertension

authors： Langford HG,Curb JD,Pressel S,Schneider KA

更新日期：1991-08-01 00:00:00

abstract：:Physical exercise can increase urinary albumin excretion rate (UAER) in diabetic patients without microalbuminuria at rest (stage II diabetic nephropathy) or with baseline microalbuminuria (stage III diabetic nephropathy). The aim of this study was to compare the acute effects of captopril, an ACE inhibitor, and nifed...

journal_title：Journal of human hypertension

authors： Romanelli G,Giustina A,Cravarezza P,Caldonazzo A,Agabiti-Rosei E,Giustina G

更新日期：1991-06-01 00:00:00

abstract：:In a double-blind, parallel-group multicentre study in general practice, lisinopril (10-20 mg once daily) was compared with metoprolol (100-200 mg once daily) in 360 patients whose diastolic blood pressure (DBP) was in the range 91-115 mmHg despite diuretic treatment. Following a three week run-in period during which ...

journal_title：Journal of human hypertension

authors： Frimodt-Moeller J,Poulsen DL,Kornerup HJ,Bech P

更新日期：1991-06-01 00:00:00

abstract：:The accuracy of the TM-2420 ambulatory blood pressure monitor (A&D Co, Japan) has been assessed by the indirect method according to the recommendations of the Association for the Advancement of Medical Instrumentation (AAMI). Ninety subjects (43 men and 47 women), aged 19-89 with a range of systolic blood pressures (S...

journal_title：Journal of human hypertension

authors： Clark S,Fowlie S,Coats A,Radaelli A,van der Putt M,Bird R,Conway J

更新日期：1991-04-01 00:00:00

abstract：:Large differences exist within populations in the dietary intake of nutrients between men and women and these differences are still largely unknown. Using data obtained from the Intersalt study and from other relevant epidemiological studies, the sex ratio of the 24 h urinary excretion of different cations was obtaine...

journal_title：Journal of human hypertension

authors： Kesteloot H,Elliott P,Lesaffre E

更新日期：1990-12-01 00:00:00

abstract：:The effects of propranolol and diltiazem on left ventricular systolic and diastolic function in hypertensive subjects (DBP 90-114 mmHg) were examined with M-mode and 2D echocardiograms in 21 patients in a double-blind fashion prior to and after 4 months of treatment. Systolic function was assessed by measurement of fr...

journal_title：Journal of human hypertension

authors： Ramanathan KB,Ratts TE,Griffin B,Sullivan JM

更新日期：1990-12-01 00:00:00

abstract：:Sudden death has been shown to be due in the majority of cases to ventricular arrhythmia. Left ventricular hypertrophy (LVH) may be implicated in the aetiology of some arrhythmia and sudden death. Recent evidence suggests that the relationship between LVH and arrhythmia may be complex and that there may be an interact...

journal_title：Journal of human hypertension

authors： Jones JV,James MA

更新日期：1990-10-01 00:00:00

abstract：:Hyperglycaemia, a raised fibrinogen, an increased serum triglyceride and a reduced HDL-cholesterol are common metabolic features of non-insulin dependent diabetes mellitus (NIDDM). Hypertension is frequently associated with NIDDM, however the influence of antihypertensive therapy on these combined factors in the diabe...

journal_title：Journal of human hypertension

authors： Feher MD,Henderson AD,Wadsworth J,Poulter C,Gelding S,Richmond W,Sever PS,Elkeles RS

更新日期：1990-10-01 00:00:00

abstract：:To identify the prevalence and magnitude of clinic changes in blood pressure and determine their effects on the diagnosis and treatment of hypertension, 268 patients with a BP greater than or equal to 160/95 mmHg on three consecutive occasions (twice in the general practitioner's surgery and once in the hospital clini...

journal_title：Journal of human hypertension

authors： Hall CL,Higgs CM,Notarianni L

更新日期：1990-10-01 00:00:00

abstract：:A blood pressure recording is strictly speaking only relevant for the circumstances under which it is measured. There is increasing evidence that ambulatory recordings have more predictive power than casual BP recordings and are a better discriminator between high and low risk groups of patients, particularly within t...

journal_title：Journal of human hypertension

authors： Littler WA,West JW

更新日期：1990-10-01 00:00:00